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KMID : 0861020220370060029
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Korea Journal of Herbology
2022 Volume.37 No. 6 p.29 ~ p.36
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Vasorelaxant or hypotensive effects of herbal medicines belong to Umbelliferae family: a review
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Kim Bum-Jung
Choi Ho-Young
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Abstract
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Objectives : The objective of this study was to investigate the possibility for the treatment of hypertension of herbal
medicines belong to Umbelliferae family.
Methods : Domestic and international articles about Herbology were investigated. A review was performed via the
database (DB) search engines such as Pubmed, Korean studies Information Service System (KISS), KoreaScience, and
Google Scholar. Hypertension-related terms including “vasorelaxation”, “vasorelaxant”, “vasodilation”, “vasodilatory”, “vasodilative”, “hypotension”, and “hypotensive” were performed as search terms.
Results : A list was made about herbal medicines and origin plants belonging to the Umbelliferae family in Korean
Pharmacopoeia 12 and Korean Herbal Pharmacopoeia. 14 herbal medicine and 22 origin plants were searched.
Ostericum koreanum root and rhizome, Notopterygium incisum root and rhizome, N. forbesii root and rhizome,
Ligusticum tenuissimum root and rhizome, L. jeholense root and rhizome, Angelica gigas root, A. dahurica root, A.
dahurica var. formosana root, Bupleurum falcatum root, Peucedanum japonicum root, P. praeruptorum root, A.
decursiva root, Cnidium officinale rhizome, L. chuanxiong rhizome, Foeniculum vulgare fruit, and Ferula assa-foetida
resin and stem showed significant vasorelaxant or hypotensive effects.
Conclusion : These review results showed that Osterici seu Notopterygii Radix et Rhizoma, Ligustici Tenuissimi
Rhizoma et Radix, Angelicae Gigantis Radix, Angelicae Dahuricae Radix, Bupleuri Radix, Peucedani Japonici Radix,
Peucedani Radix, Cnidii Rhizoma, Foeniculi Fructus, and Ferulae Resina had vasorelaxant or hypotensive effects.
The results are expected as basic data in clinical trials and experimental researches for the treatment of hypertension
of herbal medicines. 1
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KEYWORD
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Umbelliferae, Apiaceae, herbal medicine, hypertension, vasorelaxation
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